Gene: SARS1

Alternate names for this Gene: NEDMAS|SARS|SERRS|SERS

Gene Summary: This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. Multiple alternatively spliced transcript variants have been described but the biological validity of all variants is unknown.

Gene is located in Chromosome: 1

Location in Chromosome : 1p13.3

Description of this Gene: seryl-tRNA synthetase 1

Type of Gene: protein-coding

rs4268379 in SARS1 gene and Coronary Artery Disease PMID 23202125 2013 Large-scale association analysis identifies new risk loci for coronary artery disease.

rs1553178049 in SARS1 gene and NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, ATAXIA, AND SEIZURES PMID 28236339 2017 Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.