Gene: SASH1

Alternate names for this Gene: CAPOK|DUH1|SH3D6A|dJ323M4.1

Gene Summary: This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.

Gene is located in Chromosome: 6

Location in Chromosome : 6q24.3-q25.1

Description of this Gene: SAM and SH3 domain containing 1

Type of Gene: protein-coding

Gene: CYP51A1P3

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs9390573 in SASH1;CYP51A1P3 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.