Gene: SCARF1

Alternate names for this Gene: SREC|SREC-I|SREC1

Gene Summary: The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells. It regulates the uptake of chemically modified low density lipoproteins, including acetylated low density lipoprotein (Ac-LDL), and it may be involved in atherogenesis. This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.3

Description of this Gene: scavenger receptor class F member 1

Type of Gene: protein-coding

rs3744644 in SCARF1 gene and Intracranial Aneurysm PMID 30823506 2019 Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population.

rs8072430 in SCARF1 gene and Low density lipoprotein cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs8072430 in SCARF1 gene and Serum LDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.