Gene: SCRIB
Alternate names for this Gene: CRIB1|SCRB1|SCRIB1|Vartul
Gene Summary: This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Gene is located in Chromosome: 8
Location in Chromosome : 8q24.3
Description of this Gene: scribble planar cell polarity protein
Type of Gene: protein-coding