Gene: SDK2

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.1

Description of this Gene: sidekick cell adhesion molecule 2

Type of Gene: protein-coding

rs35467001 in SDK2 gene and ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO PMID 27339598 2016 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

rs35467001 in SDK2 gene and AIDS, PROGRESSION TO PMID 27339598 2016 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

rs35467001 in SDK2 gene and HIV-1 infection PMID 27339598 2016 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

rs35467001 in SDK2 gene and HIV-1, RESISTANCE TO PMID 27339598 2016 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

rs35467001 in SDK2 gene and HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO PMID 27339598 2016 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

rs35467001 in SDK2 gene and Hepatitis C PMID 27339598 2016 A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

rs3816995 in SDK2 gene and Panic Disorder PMID 19165232 2009 Genome-wide association study of panic disorder in the Japanese population.