Gene: SENP7

Alternate names for this Gene: -

Gene Summary: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009].

Gene is located in Chromosome: 3

Location in Chromosome : 3q12.3

Description of this Gene: SUMO specific peptidase 7

Type of Gene: protein-coding