Gene: SERPINB7
Alternate names for this Gene: MEGSIN|PPKN|TP55
Gene Summary: This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 18
Location in Chromosome : 18q21.33
Description of this Gene: serpin family B member 7
Type of Gene: protein-coding
rs12964116 in
SERPINB7 gene and
Asthma
PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.
PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.
PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
rs12964116 in
SERPINB7 gene and
Childhood asthma
PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.
PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.