Gene: SERPINF1

Alternate names for this Gene: EPC-1|OI12|OI6|PEDF|PIG35

Gene Summary: This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.3

Description of this Gene: serpin family F member 1

Type of Gene: protein-coding