Gene: SF3A2

Alternate names for this Gene: PRP11|PRPF11|SAP62|SF3a66

Gene Summary: This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.3

Description of this Gene: splicing factor 3a subunit 2

Type of Gene: protein-coding