Gene: SFTPD

Alternate names for this Gene: COLEC7|PSP-D|SFTP4|SP-D

Gene Summary: The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism.

Gene is located in Chromosome: 10

Location in Chromosome : 10q22.3

Description of this Gene: surfactant protein D

Type of Gene: protein-coding

rs3923564 in SFTPD gene and Chronic Obstructive Airway Disease PMID 23144326 2012 Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.

PMID 28166215 2017 Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.

PMID 30804561 2019 Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

rs726288 in SFTPD gene and Rheumatoid Arthritis PMID 30423114 2019 Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.

PMID 24390342 2014 Genetics of rheumatoid arthritis contributes to biology and drug discovery.

rs3923564 in SFTPD gene and Surfactant protein D measurement PMID 23144326 2012 Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.