Gene: SGPP2

Alternate names for this Gene: SPP2|SPPase2

Gene Summary: The protein encoded by this gene is a transmembrane protein that degrades the bioactive signaling molecule sphingosine 1-phosphate. The encoded protein is induced during inflammatory responses and has been shown to be downregulated by the microRNA-31 tumor suppressor. Alternative splice variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2q36.1

Description of this Gene: sphingosine-1-phosphate phosphatase 2

Type of Gene: protein-coding

rs12614577 in SGPP2 gene and Personality Traits PMID 21173776 2012 Meta-analysis of genome-wide association studies for personality.