Gene: SH2D1B

Alternate names for this Gene: EAT2

Gene Summary: By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF484964.1, AK097162.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2163105, SAMN01820691 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367929.3/ ENSP00000356906.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.3

Description of this Gene: SH2 domain containing 1B

Type of Gene: protein-coding