Gene: SLA

Alternate names for this Gene: SLA1|SLAP

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.22

Description of this Gene: Src like adaptor

Type of Gene: protein-coding

Gene: TG

Alternate names for this Gene: AITD3|TGN

Gene Summary: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.22

Description of this Gene: thyroglobulin

Type of Gene: protein-coding