Gene: SLA2

Alternate names for this Gene: C20orf156|MARS|SLAP-2|SLAP2

Gene Summary: This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 20

Location in Chromosome : 20q11.23

Description of this Gene: Src like adaptor 2

Type of Gene: protein-coding

rs55804368 in SLA2 gene and Suntan PMID 29739929 2018 Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.