Gene: SLAMF8

Alternate names for this Gene: BLAME|CD353|SBBI42

Gene Summary: This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.2

Description of this Gene: SLAM family member 8

Type of Gene: protein-coding

rs34687326 in SLAMF8 gene and Crohn Disease PMID 28067908 2017 Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.