Gene: SLC25A10

Alternate names for this Gene: DIC|MTDPS19

Gene Summary: This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: solute carrier family 25 member 10

Type of Gene: protein-coding

rs1555703272 in SLC25A10 gene and Decreased activity of mitochondrial complex I PMID 29211846 2018 SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency.

rs1555703272 in SLC25A10 gene and Epileptic encephalopathy PMID 29211846 2018 SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency.

rs1555703272 in SLC25A10 gene and Infantile muscular hypotonia PMID 29211846 2018 SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency.

rs1555703272 in SLC25A10 gene and MITOCHONDRIAL COMPLEX I DEFICIENCY PMID 29211846 2018 SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency.