Gene: SLC2A9

Alternate names for this Gene: GLUT9|GLUTX|UAQTL2|URATv1

Gene Summary: This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.1

Description of this Gene: solute carrier family 2 member 9

Type of Gene: protein-coding

Gene: LOC105374476

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs10008035 in SLC2A9;LOC105374476 gene and Arthritis, Gouty PMID 20884846 2010 Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.

PMID 23263486 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

PMID 21768215 2011 Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

PMID 31289104 2019 Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.

PMID 27899376 2017 GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.

rs10008035 in SLC2A9;LOC105374476 gene and Gout PMID 23263486 2013 Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

PMID 20884846 2010 Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.

PMID 21768215 2011 Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

PMID 31289104 2019 Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout.

PMID 27899376 2017 GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.

rs13111638 in SLC2A9;LOC105374476 gene and Kidney Failure, Chronic PMID 30181573 2018 Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease.

rs10008035 in SLC2A9;LOC105374476 gene and Uric acid measurement (procedure) PMID 19503597 2009 Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

PMID 30181573 2018 Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease.

PMID 21294900 2011 A genome-wide association study of serum uric acid in African Americans.

PMID 31578528 2019 Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

PMID 23703922 2013 Significant associations were found in SLC2A9 gene SNPs and plasma uric acid levels (rs6449213, P = 3.15 × 10(-12) ).

PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.

PMID 30305239 2019 Genetic contributors to serum uric acid levels in Mexicans and their effect on premature coronary artery disease.