Gene: SLC3A2

Alternate names for this Gene: 4F2|4F2HC|4T2HC|CD98|CD98HC|MDU1|NACAE

Gene Summary: This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.3

Description of this Gene: solute carrier family 3 member 2

Type of Gene: protein-coding

rs144453006 in SLC3A2 gene and Transferrin saturation measurement PMID 28334935 2017 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?