Gene: SLCO1B3-SLCO1B7

Alternate names for this Gene: LST-3TM12|OATP1B3-1B7

Gene Summary: This locus represents naturally occurring readthrough transcription between the neighboring SLCO1B3 (solute carrier organic anion transporter family member 1B3) and SLCO1B7 (solute carrier organic anion transporter family member 1B7 (putative)) genes on chromosome 12. The readthrough transcript encodes a protein that shares sequence identity with both the upstream and downstream genes.

Gene is located in Chromosome: 12

Location in Chromosome : 12p12.2

Description of this Gene: SLCO1B3-SLCO1B7 readthrough

Type of Gene: protein-coding

Gene: SLCO1B3

Alternate names for this Gene: HBLRR|LST-2|LST-3TM13|LST3|OATP-8|OATP1B3|OATP8|SLC21A8

Gene Summary: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity.

Gene is located in Chromosome: 12

Location in Chromosome : 12p12.2

Description of this Gene: solute carrier organic anion transporter family member 1B3

Type of Gene: protein-coding