Gene: SMG6

Alternate names for this Gene: C17orf31|EST1A|SMG-6|hSMG5/7a

Gene Summary: This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.3

Description of this Gene: SMG6 nonsense mediated mRNA decay factor

Type of Gene: protein-coding

Gene: LOC101927839

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.3

Description of this Gene: uncharacterized LOC101927839

Type of Gene: ncRNA

rs7217226 in SMG6;LOC101927839 gene and Body mass index PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs7217226 in SMG6;LOC101927839 gene and Waist-Hip Ratio PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.