Gene: SNIP1

Alternate names for this Gene: PML1|PMRED

Gene Summary: This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).

Gene is located in Chromosome: 1

Location in Chromosome : 1p34.3

Description of this Gene: Smad nuclear interacting protein 1

Type of Gene: protein-coding