Gene: SNORD83A

Alternate names for this Gene: RNU83A|U83A

Gene Summary: Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83A, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83A, function in 2-prime-O-ribose methylation of rRNAs (Duga et al., 2000 [PubMed 10684968]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: small nucleolar RNA, C/D box 83A

Type of Gene: snoRNA

Gene: SNORD83B

Alternate names for this Gene: RNU83B|U83B

Gene Summary: Intronic regions of ribosomal protein genes can harbor noncoding small nucleolar RNAs (snoRNAs), like SNORD83B, which are generated during pre-mRNA processing. snoRNAs form part of the small nucleolar ribonucleoprotein particles (snoRNPs) involved in pre-rRNA processing and modification. snoRNAs of the box C/D class, like SNORD83B, function in 2-prime-O-ribose methylation of rRNAs (Duga et al., 2000 [PubMed 10684968]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: small nucleolar RNA, C/D box 83B

Type of Gene: snoRNA

Gene: RPL3

Alternate names for this Gene: ASC-1|L3|TARBP-B

Gene Summary: Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: ribosomal protein L3

Type of Gene: protein-coding

rs2076125 in SNORD83A;SNORD83B;RPL3 gene and Primary biliary cirrhosis PMID 21399635 2011 Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.