Gene: SNRPA

Alternate names for this Gene: Mud1|U1-A|U1A

Gene Summary: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.2

Description of this Gene: small nuclear ribonucleoprotein polypeptide A

Type of Gene: protein-coding

rs2279011 in SNRPA gene and Forced expiratory volume function PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

rs11665867 in SNRPA gene and Hematocrit procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.