Gene: SNX19

Alternate names for this Gene: CHET8

Gene Summary: Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles.

Gene is located in Chromosome: 11

Location in Chromosome : 11q24.3-q25

Description of this Gene: sorting nexin 19

Type of Gene: protein-coding

rs4459316 in SNX19 gene and Body mass index PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.