Gene: SOCS4

Alternate names for this Gene: SOCS7

Gene Summary: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 14

Location in Chromosome : 14q22.3

Description of this Gene: suppressor of cytokine signaling 4

Type of Gene: protein-coding

Gene: WDHD1

Alternate names for this Gene: AND-1|AND1|CHTF4|CTF4

Gene Summary: The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms.

Gene is located in Chromosome: 14

Location in Chromosome : 14q22.2-q22.3

Description of this Gene: WD repeat and HMG-box DNA binding protein 1

Type of Gene: protein-coding

rs1187878 in SOCS4;WDHD1 gene and Protein measurement PMID 23056639 2012 A genome-wide association study of circulating galectin-3.