Gene: SOX15

Alternate names for this Gene: SOX20|SOX26|SOX27

Gene Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: SRY-box transcription factor 15

Type of Gene: protein-coding

Gene: MPDU1

Alternate names for this Gene: CDGIF|HBEBP2BPA|Lec35|My008|PP3958|PQLC5|SL15|SLC66A5

Gene Summary: This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: mannose-P-dolichol utilization defect 1

Type of Gene: protein-coding

rs4227 in SOX15;MPDU1 gene and IGA Glomerulonephritis PMID 22197929 2011 A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy.

rs4227 in SOX15;MPDU1 gene and Testosterone measurement PMID 31169883 2019 Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease.