Gene: SP2

Alternate names for this Gene: -

Gene Summary: This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: Sp2 transcription factor

Type of Gene: protein-coding

Gene: SP2-AS1

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: SP2 antisense RNA 1

Type of Gene: ncRNA

rs16949418 in SP2;SP2-AS1 gene and Hair Color PMID 30531825 2018 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.