Gene: SPC25

Alternate names for this Gene: AD024|SPBC25|hSpc25

Gene Summary: This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity.

Gene is located in Chromosome: 2

Location in Chromosome : 2q24.3

Description of this Gene: SPC25 component of NDC80 kinetochore complex

Type of Gene: protein-coding

rs10497345 in SPC25 gene and Fasting blood glucose measurement PMID 31021400 2019 Pleiotropy informed adaptive association test of multiple traits using genome-wide association study summary data.

PMID 25187374 2015 Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.

PMID 29621232 2018 Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.

PMID 30327367 2019 Genome-Wide Meta-analysis of Gene-Environmental Interaction for Insulin Resistance Phenotypes and Breast Cancer Risk in Postmenopausal Women.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

rs13431652 in SPC25 gene and Fatty acid measurement PMID 30327367 2019 Genome-Wide Meta-analysis of Gene-Environmental Interaction for Insulin Resistance Phenotypes and Breast Cancer Risk in Postmenopausal Women.

rs12053049 in SPC25 gene and Glucose measurement PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

rs12475700 in SPC25 gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

rs12053049 in SPC25 gene and elevated blood glucose level PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.