Gene: SPG11
Alternate names for this Gene: ALS5|CMT2X|KIAA1840
Gene Summary: The protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 15
Location in Chromosome : 15q21.1
Description of this Gene: SPG11 vesicle trafficking associated, spatacsin
Type of Gene: protein-coding
Gene: EIF3J
Alternate names for this Gene: EIF3S1|eIF3-alpha|eIF3-p35
Gene Summary: This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome. There are pseudogenes for this gene on chromosomes 1, 3, and 9. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene is located in Chromosome: 15
Location in Chromosome : 15q21.1
Description of this Gene: eukaryotic translation initiation factor 3 subunit J
Type of Gene: protein-coding