Gene: SPIRE1

Alternate names for this Gene: Spir-1

Gene Summary: Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 18

Location in Chromosome : 18p11.21

Description of this Gene: spire type actin nucleation factor 1

Type of Gene: protein-coding

rs1940973 in SPIRE1 gene and Cytokine Measurement PMID 22542470 2012 Genome-wide association study of antibody response to smallpox vaccine.

rs146223307 in SPIRE1 gene and Red Blood Cell Count measurement PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.