Gene: SPNS1

Alternate names for this Gene: HSpin1|LAT|PP2030|SLC62A1|SLC63A1|SPIN1|SPINL|nrs

Gene Summary:

Gene is located in Chromosome: 16

Location in Chromosome : 16p11.2

Description of this Gene: sphingolipid transporter 1 (putative)

Type of Gene: protein-coding

Gene: LAT

Alternate names for this Gene: IMD52|LAT1|pp36

Gene Summary: The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 16

Location in Chromosome : 16p11.2

Description of this Gene: linker for activation of T cells

Type of Gene: protein-coding