Gene: SPRYD4

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.3

Description of this Gene: SPRY domain containing 4

Type of Gene: protein-coding

Gene: MIP

Alternate names for this Gene: AQP0|CTRCT15|LIM1|MIP26|MP26

Gene Summary: Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.3

Description of this Gene: major intrinsic protein of lens fiber

Type of Gene: protein-coding

rs7302925 in SPRYD4;MIP gene and Amino acids measurement PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs73114872 in SPRYD4;MIP gene and Blood urea nitrogen measurement PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.

rs7302925 in SPRYD4;MIP gene and Glutamine measurement PMID 30659259 2019 Genetic basis for plasma amino acid concentrations based on absolute quantification: a genome-wide association study in the Japanese population.

rs7302925 in SPRYD4;MIP gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.