Gene: SPTLC3

Alternate names for this Gene: C20orf38|LCB 3|LCB2B|LCB3|SPT 3|SPT3|SPTLC2L|dJ718P11|dJ718P11.1|hLCB2b

Gene Summary: This gene encodes a subunit of the serine palmitoyltransferase complex which catalyzes the rate-limiting step in sphingolipid biosynthesis. This subunit metabolizes lauroyl- and myristoyl-CoA and generates C14 and C16-sphingoid bases.

Gene is located in Chromosome: 20

Location in Chromosome : 20p12.1

Description of this Gene: serine palmitoyltransferase long chain base subunit 3

Type of Gene: protein-coding

Gene: TASP1

Alternate names for this Gene: C20orf13|SULEHS|dJ585I14.2

Gene Summary: This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene is located in Chromosome: 20

Location in Chromosome : 20p12.1

Description of this Gene: taspase 1

Type of Gene: protein-coding