Gene: SPTLC3

Alternate names for this Gene: C20orf38|LCB 3|LCB2B|LCB3|SPT 3|SPT3|SPTLC2L|dJ718P11|dJ718P11.1|hLCB2b

Gene Summary: This gene encodes a subunit of the serine palmitoyltransferase complex which catalyzes the rate-limiting step in sphingolipid biosynthesis. This subunit metabolizes lauroyl- and myristoyl-CoA and generates C14 and C16-sphingoid bases.

Gene is located in Chromosome: 20

Location in Chromosome : 20p12.1

Description of this Gene: serine palmitoyltransferase long chain base subunit 3

Type of Gene: protein-coding

rs755919784 in SPTLC3 gene and Peripheral Neuropathy PMID 26257172 2015 Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy.

rs755919784 in SPTLC3 gene and Sensory neuropathy PMID 26257172 2015 Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy.