Gene: SPTSSB

Alternate names for this Gene: ADMP|C3orf57|SSSPTB

Gene Summary: Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010].

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.1

Description of this Gene: serine palmitoyltransferase small subunit B

Type of Gene: protein-coding