Gene: SRA1

Alternate names for this Gene: SRA|SRAP|STRAA1|pp7684

Gene Summary: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.3

Description of this Gene: steroid receptor RNA activator 1

Type of Gene: protein-coding

rs6889768 in SRA1 gene and Malignant neoplasm of prostate PMID 24185611 2014 A genome-wide association study of prostate cancer in West African men.