Gene: SRPRB

Alternate names for this Gene: APMCF1|SR-beta

Gene Summary: The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.

Gene is located in Chromosome: 3

Location in Chromosome : 3q22.1

Description of this Gene: SRP receptor subunit beta

Type of Gene: protein-coding

Gene: TF

Alternate names for this Gene: HEL-S-71p|PRO1557|PRO2086|TFQTL1

Gene Summary: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.

Gene is located in Chromosome: 3

Location in Chromosome : 3q22.1

Description of this Gene: transferrin

Type of Gene: protein-coding

rs9843728 in SRPRB;TF gene and Alcohol consumption PMID 21665994 2011 Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.

rs9843728 in SRPRB;TF gene and Finding of Mean Corpuscular Hemoglobin PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.