Gene: ST20

Alternate names for this Gene: HCCS-1

Gene Summary:

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.1

Description of this Gene: suppressor of tumorigenicity 20

Type of Gene: ncRNA

Gene: ST20-MTHFS

Alternate names for this Gene: MTHFS

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring suppressor of tumorigenicity 20 and 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) genes on chromosome 15. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.1

Description of this Gene: ST20-MTHFS readthrough

Type of Gene: protein-coding

Gene: MTHFS

Alternate names for this Gene: HsT19268|NEDMEHM

Gene Summary: The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.1

Description of this Gene: methenyltetrahydrofolate synthetase

Type of Gene: protein-coding