Gene: ST6GAL2

Alternate names for this Gene: SIAT2|ST6GalII

Gene Summary: This locus encodes a sialyltransferase. The encoded type II transmembrane protein catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. Polymorphisms at this locus may be associated with variations in risperidone response in schizophrenic patients. Alternatively spliced transcript variants have been described.

Gene is located in Chromosome: 2

Location in Chromosome : 2q12.3

Description of this Gene: ST6 beta-galactoside alpha-2,6-sialyltransferase 2

Type of Gene: protein-coding

rs10191793 in ST6GAL2 gene and Esophageal Neoplasms PMID 22960999 2012 Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.

rs1034811 in ST6GAL2 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.