Gene: ST8SIA1

Alternate names for this Gene: GD3S|SIAT8|SIAT8-A|SIAT8A|ST8SiaI

Gene Summary: Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12p12.1

Description of this Gene: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Type of Gene: protein-coding