Gene: STEAP3

Alternate names for this Gene: AHMIO2|STMP3|TSAP6|dudlin-2|dudulin-2|pHyde

Gene Summary: This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 2

Location in Chromosome : 2q14.2

Description of this Gene: STEAP3 metalloreductase

Type of Gene: protein-coding

rs13027293 in STEAP3 gene and Renal Cell Carcinoma PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.