Gene: STIMATE-MUSTN1

Alternate names for this Gene: TMEM110-MUSTN1

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring TMEM110 (transmembrane protein 110) and MUSTN1 (musculoskeletal, embryonic nuclear protein 1) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: STIMATE-MUSTN1 readthrough

Type of Gene: protein-coding

Gene: MIR8064

Alternate names for this Gene: hsa-mir-8064

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: microRNA 8064

Type of Gene: ncRNA

Gene: STIMATE

Alternate names for this Gene: TMEM110

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: STIM activating enhancer

Type of Gene: protein-coding

rs6445541 in STIMATE-MUSTN1;MIR8064;STIMATE gene and Anxiety PMID 29942085 2018 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.