Gene: STK24

Alternate names for this Gene: HEL-S-95|MST3|MST3B|STE20|STK3

Gene Summary: This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 13

Location in Chromosome : 13q32.2

Description of this Gene: serine/threonine kinase 24

Type of Gene: protein-coding

Gene: FARP1

Alternate names for this Gene: CDEP|FARP1-IT1|PLEKHC2|PPP1R75

Gene Summary: This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 13

Location in Chromosome : 13q32.2

Description of this Gene: FERM, ARH/RhoGEF and pleckstrin domain protein 1

Type of Gene: protein-coding

rs12869774 in STK24;FARP1 gene and Bone Mineral Density Test PMID 21124946 2010 Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone.