Gene: SUMO2

Alternate names for this Gene: HSMT3|SMT3B|SMT3H2|SUMO3|Smt3A

Gene Summary: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.1

Description of this Gene: small ubiquitin like modifier 2

Type of Gene: protein-coding