Gene: SYCP2L

Alternate names for this Gene: C6orf177|NO145|dJ62D2.1

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p24.2

Description of this Gene: synaptonemal complex protein 2 like

Type of Gene: protein-coding

rs1225764 in SYCP2L gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs6899676 in SYCP2L gene and Age at menarche PMID 29773799 2018 Elucidating the genetic architecture of reproductive ageing in the Japanese population.

rs12211124 in SYCP2L gene and Age at menopause PMID 29773799 2018 Elucidating the genetic architecture of reproductive ageing in the Japanese population.

PMID 22267201 2012 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

PMID 19448621 2009 Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.

PMID 26414677 2015 Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs4713039 in SYCP2L gene and Allergic rhinitis (disorder) PMID 25085501 2014 Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.

rs2788869 in SYCP2L gene and Antiphospholipid Syndrome PMID 28424481 2017 The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome.

rs2295599 in SYCP2L gene and Chronic Obstructive Airway Disease PMID 26503814 2016 A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease.

rs12190237 in SYCP2L gene and Phospholipid measurement PMID 21829377 2011 Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

rs1225764 in SYCP2L gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.