Gene: SYT6

Alternate names for this Gene: sytVI

Gene Summary: The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p13.2

Description of this Gene: synaptotagmin 6

Type of Gene: protein-coding

rs12732487 in SYT6 gene and Venous Thromboembolism PMID 31420334 2019 Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.