Gene: SYTL3

Alternate names for this Gene: SLP3

Gene Summary: The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.3

Description of this Gene: synaptotagmin like 3

Type of Gene: protein-coding

rs2171209 in SYTL3 gene and Ankle brachial pressure index (observable entity) PMID 22361517 2012 In the European ancestry discovery meta-analyses, rs2171209 in SYTL3 (β=-0.007, p=6.02×10(-7)) and rs290481 in TCF7L2 (β=-0.008, p=7.01×10(-7)) were significantly associated with ABI.

rs1979541 in SYTL3 gene and Lipoprotein (a) measurement PMID 26377243 2015 Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study.

rs317789 in SYTL3 gene and Peripheral Arterial Diseases PMID 31388106 2019 Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos.