Gene: TACC3

Alternate names for this Gene: ERIC-1|ERIC1|Tacc4|maskin

Gene Summary: This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.3

Description of this Gene: transforming acidic coiled-coil containing protein 3

Type of Gene: protein-coding

Gene: SLBP

Alternate names for this Gene: HBP

Gene Summary: This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.3

Description of this Gene: stem-loop binding protein

Type of Gene: protein-coding

rs798748 in TACC3;SLBP gene and Osteoarthritis of hip PMID 30664745 2019 Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data.