Gene: TAOK2
Alternate names for this Gene: MAP3K17|PSK|PSK1|PSK1-BETA|TAO1|TAO2
Gene Summary: This gene encodes a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene is located in Chromosome: 16
Location in Chromosome : 16p11.2
Description of this Gene: TAO kinase 2
Type of Gene: protein-coding
rs3814883 in
TAOK2 gene and
Body mass index
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 29273807 2018 Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
rs3814883 in
TAOK2 gene and
Intelligence
PMID 31374203 2019 Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
rs4583255 in
TAOK2 gene and
Psychotic Disorders
PMID 23164818 2014 Common variant at 16p11.2 conferring risk of psychosis.
rs3814881 in
TAOK2 gene and
Schizophrenia
PMID 30285260 2019 Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
PMID 28991256 2017 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
PMID 31374203 2019 Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
rs4788204 in
TAOK2 gene and
Waist-Hip Ratio
PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.