Gene: TAPBP

Alternate names for this Gene: NGS17|TAPA|TPN|TPSN

Gene Summary: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.32

Description of this Gene: TAP binding protein

Type of Gene: protein-coding

Gene: ZBTB22

Alternate names for this Gene: BING1|ZBTB22A|ZNF297|ZNF297A|fru|fruitless

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.32

Description of this Gene: zinc finger and BTB domain containing 22

Type of Gene: protein-coding